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2007
VerseesW, SpaepenS, VanderleydenJ, SteyaertJ.  2007.  The crystal structure of phenylpyruvate decarboxylase from Azospirillum brasilense at 1.5 A resolution. Implications for its catalytic and regulatory mechanism. FEBS J. 274(9):2363-2375. Abstract
2006
RoosG, ButsL, VanBelle K, BrosensE, GeerlingsP, LorisR, WynsL, MessensJ.  2006.  Interplay between ion binding and catalysis in the thioredoxin-coupled arsenate reductase family. J. Mol. Biol.. 360(4):826-838. Abstract
VerseesW, BarlowJ, SteyaertJ.  2006.  Transition-state complex of the purine-specific nucleoside hydrolase of T. vivax: enzyme conformational changes and implications for catalysis. Journal Molecular Biology. 359(2):331-346. Abstract
RoosG, LoverixS, BrosensE, VanBelle K, WynsL, GeerlingsP, MessensJ.  2006.  The activation of electrophile, nucleophile and leaving group during the reaction catalysed by pI258 arsenate reductase. Chembiochem.. 7(6):981-989. Abstract
MessensJ, ColletJF.  2006.  Pathways of disulfide bond formation in Escherichia coli. Int. J. Biochem. Cell Biol.. 38(7):1050-1062. Abstract
2005
LoverixS, GeerlingsP, McNaughtonM, AugustynsK, VandemeulebrouckeA, SteyaertJ, VerseesW.  2005.  Substrate-assisted leaving group activation in enzyme-catalyzed N-glycosidic bond cleavage. J. Biol. Chem. 280(15):14799-14802. Abstract
HuysmansG, RanquinA, WynsL, SteyaertJ, VanGelder P.  2005.  Encapsulation of therapeutic nucleoside hydrolase in functionalised nanocapsules. J Control Release. 102(1):171-179. Abstract
2004
VerseesW, LoverixS, VandemeulebrouckeA, GeerlingsP, SteyaertJ.  2004.  Leaving group activation by aromatic stacking: an alternative to general acid catalysis. J. Mol. Biol. 338(1):1-6. Abstract
2003
VerseesW, SteyaertJ.  2003.  Catalysis by nucleoside hydrolases. Current opinion in structural biology. 13(6):731-738. Abstract
LoverixS, SteyaertJ.  2003.  Ribonucleases: from prototypes to therapeutic targets?. Current Medicinal Chemistry. 10(9):779-785. Abstract
2002
MessensJ, MartinsJC, VanBelle K, BrosensE, DesmyterA, DeGieter M, WieruszeskiJM, WillemR, WynsL, ZegersI.  2002.  All intermediates of the arsenate reductase mechanism, including an intramolecular dynamic disulfide cascade. Proc. Natl. Acad. Sci. USA. 99(13):8506-8511. Abstract
VerseesW, DecanniereK, VanHolsbeke E, DevroedeN, SteyaertJ.  2002.  Enzyme-substrate interactions in the purine-specific nucleoside hydrolase from Trypanosoma vivax. J. Biol. Chem. 277(18):15938-15946. Abstract
2001
ZegersI, MartinsJC, WillemR, WynsL, MessensJ.  2001.  Arsenate reductase from S. aureus plasmid pI258 is a phosphatase drafted for redox duty. Nat. Struct. Biol.. 8(10):843-847. Abstract
LoverixS, SteyaertJ.  2001.  Deciphering the mechanism of RNase T1. 341:305-323.
2000
LoverixS, WinqvistA, StrombergR, SteyaertJ.  2000.  Mechanism of RNase T1: concerted triester-like phosphoryl transfer via a catalytic three-centered hydrogen bond. 7(8):651-658. Abstract
1999
MessensJ, HayburnG, DesmyterA, LausG, WynsL.  1999.  The essential catalytic redox couple in arsenate reductase from Staphylococcus aureus. Biochemistry. 38(51):16857-16865. Abstract
1998
LoverixS, LausG, MartinsJC, WynsL, SteyaertJ.  1998.  Reconsidering the energetics of ribonuclease catalysed RNA hydrolysis. 257(1):286-290. Abstract
LoverixS, LausG, MartinsJC, WynsL, SteyaertJ.  1998.  Reconsidering the energetics of ribonuclease catalysed RNA hydrolysis. 257(1):286-290. Abstract
LoverixS, WinquistA, StrombergR, SteyaertJ.  1998.  An engineered ribonuclease preferring phosphorothioate RNA. 5(5):365-368. Abstract
AlvarezM, ZeelenJP, MainfroidV, Rentier-DelrueF, MartialJA, WynsL, WierengaRK, MaesD.  1998.  Triose-phosphate isomerase (TIM) of the psychrophilic bacterium Vibrio marinus. Kinetic and structural properties. 273(4):2199-2206. Abstract
1996
DoumenJ, GonciarzM, ZegersI, LorisR, WynsL, SteyaertJ.  1996.  A catalytic function for the structurally conserved residue Phe 100 of ribonuclease T1. 5(8):1523-1530. Abstract
DoumenJ, GonciarzM, ZegersI, LorisR, WynsL, SteyaertJ.  1996.  A catalytic function for the structurally conserved residue Phe 100 of ribonuclease T1. 5(8):1523-1530. Abstract
1994
SteyaertJ, HaikalAF, WynsL.  1994.  Investigation of the functional interplay between the primary site and the subsite of RNase T1: kinetic analysis of single and multiple mutants for modified substrates. 18(4):318-323. Abstract
SteyaertJ, HaikalAF, WynsL.  1994.  Investigation of the functional interplay between the primary site and the subsite of RNase T1: kinetic analysis of single and multiple mutants for modified substrates. 18(4):318-323. Abstract
1993
SteyaertJ, WynsL.  1993.  Functional interactions among the His40, Glu58 and His92 catalysts of ribonuclease T1 as studied by double and triple mutants. 229(3):770-781. Abstract