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2007
DeJonge N, ButsL, VangeloovenJ, MineN, VanMelderen L, WynsL, LorisR.  2007.  Purification and crystallization of Vibrio fischeri CcdB and its complexes with fragments of gyrase and CcdA. 63(Pt 4):356-360. Abstract
2005
ButsL, LahJ, Dao-ThiMH, WynsL, LorisR.  2005.  Toxin-antitoxin modules as bacterial metabolic stress managers. 30(12):672-679. Abstract
Dao-ThiMH, VanMelderen L, DeGenst E, AfifH, ButsL, WynsL, LorisR.  2005.  Molecular basis of gyrase poisoning by the addiction toxin CcdB. 348(5):1091-1102. Abstract
LahJ, SimicM, VesnaverG, MarianovskyI, GlaserG, Engelberg-KulkaH, LorisR.  2005.  Energetics of structural transitions of the addiction antitoxin MazE: is a programmed bacterial cell death dependent on the intrinsically flexible nature of the antitoxins?. 280(17):17397-17407. Abstract
MignonP, LoverixS, SteyaertJ, GeerlingsP.  2005.  Influence of the pi-pi interaction on the hydrogen bonding capacity of stacked DNA/RNA bases. Nucleic Acids Research. 33(6):1779-1789. Abstract
2004
Dao-ThiMH, VanMelderen L, DeGenst E, ButsL, RanquinA, WynsL, LorisR.  2004.  Crystallization of CcdB in complex with a GyrA fragment. 60(Pt 6):1132-1134. Abstract
2003
LorisR, MarianovskyI, LahJ, LaeremansT, Engelberg-KulkaH, GlaserG, MuyldermansS, WynsL.  2003.  Crystal structure of the intrinsically flexible addiction antidote MazE. 278(30):28252-28257. Abstract
LahJ, MarianovskyI, GlaserG, Engelberg-KulkaH, KinneJ, WynsL, LorisR.  2003.  Recognition of the intrinsically flexible addiction antidote MazE by a dromedary single domain antibody fragment. Structure, thermodynamics of binding, stability, and influence on interactions with DNA. 278(16):14101-14111. Abstract
2002
De GreveH, QizhiC, DeboeckF, HernalsteensJP.  2002.  The Shiga-toxin VT2-encoding bacteriophage phi297 integrates at a distinct position in the Escherichia coli genome. 1579(2-3):196-202. Abstract
VerseesW, DecanniereK, VanHolsbeke E, DevroedeN, SteyaertJ.  2002.  Enzyme-substrate interactions in the purine-specific nucleoside hydrolase from Trypanosoma vivax. J. Biol. Chem. 277(18):15938-15946. Abstract
2000
Dao-ThiMH, MessensJ, WynsL, BackmannJ.  2000.  The thermodynamic stability of the proteins of the ccd plasmid addiction system. J. Mol. Biol.. 299(5):1373-1386. Abstract
1999
NguyenVK, HamersR, WynsL, MuyldermansS.  1999.  Loss of splice consensus signal is responsible for the removal of the entire C(H)1 domain of the functional camel IGG2A heavy-chain antibodies. 36(8):515-524. Abstract
BahassiEM, O'DeaMH, AllaliN, MessensJ, GellertM, CouturierM.  1999.  Interactions of CcdB with DNA gyrase. Inactivation of Gyra, poisoning of the gyrase-DNA complex, and the antidote action of CcdA. J. Biol. Chem.. 274(16):10936-10944. Abstract
LorisR, Dao-ThiMH, BahassiEM, VanMelderen L, PoortmansF, LiddingtonR, CouturierM, WynsL.  1999.  Crystal structure of CcdB, a topoisomerase poison from E. coli. 285(4):1667-1677. Abstract
1998
Dao-ThiMH, WynsL, PoortmansF, BahassiEM, CouturierM, LorisR.  1998.  Crystallization of ccdB. 54(Pt 5):975-981. Abstract
1997
VuKB, GhahroudiMA, WynsL, MuyldermansS.  1997.  Comparison of llama VH sequences from conventional and heavy chain antibodies. 34(16-17):1121-1131. Abstract
1996
DoumenJ, GonciarzM, ZegersI, LorisR, WynsL, SteyaertJ.  1996.  A catalytic function for the structurally conserved residue Phe 100 of ribonuclease T1. 5(8):1523-1530. Abstract
DoumenJ, GonciarzM, ZegersI, LorisR, WynsL, SteyaertJ.  1996.  A catalytic function for the structurally conserved residue Phe 100 of ribonuclease T1. 5(8):1523-1530. Abstract
StanssensP, BergumPW, GansemansY, JespersL, LarocheY, HuangS, MakiS, MessensJ, LauwereysM, CappelloM, HotezPJ, LastersI, VlasukGP.  1996.  Anticoagulant repertoire of the hookworm Ancylostoma caninum. Proc. Natl. Acad. Sci. USA. 93(5):2149-2154. Abstract
1995
FishWR, NkhunguluZM, MuriukiCW, NdegwaDM, Lonsdale-EcclesJD, SteyaertJ.  1995.  Primary structure and partial characterization of a life-cycle-regulated cysteine protease from Trypanosoma (Nannomonas) congolense. 161(1):125-128. Abstract
PardonE, HaezebrouckP, DeBaetselier A, HookeSD, FancourtKT, DesmetJ, DobsonCM, VanDael H, JoniauM.  1995.  A Ca(2+)-binding chimera of human lysozyme and bovine alpha-lactalbumin that can form a molten globule. 270(18):10514-10524. Abstract
JespersLS, MessensJH, DeKeyser A, EeckhoutD, Vanden BrandeI, GansemansYG, LauwereysMJ, VlasukGP, StanssensPE.  1995.  Surface expression and ligand-based selection of cDNAs fused to filamentous phage gene VI. Biotechnology (N Y). 13(4):378-382. Abstract
1994
SteyaertJ, HaikalAF, WynsL.  1994.  Investigation of the functional interplay between the primary site and the subsite of RNase T1: kinetic analysis of single and multiple mutants for modified substrates. 18(4):318-323. Abstract
SteyaertJ, HaikalAF, WynsL.  1994.  Investigation of the functional interplay between the primary site and the subsite of RNase T1: kinetic analysis of single and multiple mutants for modified substrates. 18(4):318-323. Abstract
1993
BernardP, KezdyKE, VanMelderen L, SteyaertJ, WynsL, PatoML, HigginsPN, CouturierM.  1993.  The F plasmid CcdB protein induces efficient ATP-dependent DNA cleavage by gyrase. 234(3):534-541. Abstract