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Found 4 results

Sort by:[Year][Author]
Filters: keyword is Drug Design  [Clear All Filters]
2007
GoeminneA, McNaughtonM, BalG, SurpateanuG, VanDerV, DeProl S, VerseesW, SteyaertJ, ApersS, HaemersA, AugustynsK.  2007.  1,2,3-Triazolylalkylribitol derivatives as nucleoside hydrolase inhibitors. Bioorg. & Med. Chem. Lett.. 17(9):2523-2526. Abstract
2003
LoverixS, SteyaertJ.  2003.  Ribonucleases: from prototypes to therapeutic targets?. Current Medicinal Chemistry. 10(9):779-785. Abstract
2002
VerseesW, DecanniereK, VanHolsbeke E, DevroedeN, SteyaertJ.  2002.  Enzyme-substrate interactions in the purine-specific nucleoside hydrolase from Trypanosoma vivax. J. Biol. Chem. 277(18):15938-15946. Abstract
2001
VerseesW, DecanniereK, PelleR, DepoorterJ, BrosensE, ParkinDW, SteyaertJ.  2001.  Structure and function of a novel purine specific nucleoside hydrolase from Trypanosoma vivax. 307(5):1363-1379. Abstract


Publications on

  • Bacterial adhesins
  • Biomedical targets
  • Biomolecular NMR
  • Structural enzymology
  • Toxin-antitoxin systems

Most recent publications

  • Arsenate reductase, mycothiol and mycoredoxin concert thiol/disulfide exchange
  • The zinc center influences the redox and thermodynamic properties of Escherichia coli thioredoxin 2
  • Synthesis and biochemical evaluation of guanidino-alkyl-ribitol derivatives as nucleoside hydrolase inhibitors
  • Characterization of folding the four-helix bundle protein Rop by real-time NMR


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