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Found 10 results

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Filters: keyword is Immunoglobulin Variable Region  [Clear All Filters]
2005
SaerensD, PellisM, LorisR, PardonE, DumoulinM, MatagneA, WynsL, MuyldermansS, ConrathK.  2005.  Identification of a universal VHH framework to graft non-canonical antigen-binding loops of camel single-domain antibodies. 352(3):597-607. Abstract
ConrathK, VinckeC, StijlemansB, SchymkowitzJ, DecanniereK, WynsL, MuyldermansS, LorisR.  2005.  Antigen binding and solubility effects upon the veneering of a camel VHH in framework-2 to mimic a VH. 350(1):112-125. Abstract
DeGenst E, SilenceK, GhahroudiMA, DecanniereK, LorisR, KinneJ, WynsL, MuyldermansS.  2005.  Strong in vivo maturation compensates for structurally restricted H3 loops in antibody repertoires. 280(14):14114-14121. Abstract
2004
WallJS, GuptaV, WilkersonM, SchellM, LorisR, AdamsP, SolomonA, StevensF, DealwisC.  2004.  Structural basis of light chain amyloidogenicity: comparison of the thermodynamic properties, fibrillogenic potential and tertiary structural features of four Vlambda6 proteins. 17(4):323-331. Abstract
2002
DesmyterA, SpinelliS, PayanF, LauwereysM, WynsL, MuyldermansS, CambillauC.  2002.  Three camelid VHH domains in complex with porcine pancreatic alpha-amylase. Inhibition and versatility of binding topology. 277(26):23645-23650. Abstract
2001
DecanniereK, TransueTR, DesmyterA, MaesD, MuyldermansS, WynsL.  2001.  Degenerate interfaces in antigen-antibody complexes. 313(3):473-478. Abstract
2000
DecanniereK, MuyldermansS, WynsL.  2000.  Canonical antigen-binding loop structures in immunoglobulins: more structures, more canonical classes?. 300(1):83-91. Abstract
NguyenVK, HamersR, WynsL, MuyldermansS.  2000.  Camel heavy-chain antibodies: diverse germline V(H)H and specific mechanisms enlarge the antigen-binding repertoire. 19(5):921-930. Abstract
1997
VuKB, GhahroudiMA, WynsL, MuyldermansS.  1997.  Comparison of llama VH sequences from conventional and heavy chain antibodies. 34(16-17):1121-1131. Abstract
1996
DesmyterA, TransueTR, GhahroudiMA, ThiMH, PoortmansF, HamersR, MuyldermansS, WynsL.  1996.  Crystal structure of a camel single-domain VH antibody fragment in complex with lysozyme. 3(9):803-811. Abstract