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2007
VerseesW, SpaepenS, WoodMD, LeeperFJ, VanderleydenJ, SteyaertJ.  2007.  Molecular mechanism of allosteric substrate activation in a thiamine diphosphate-dependent decarboxylase. Journal Biological Chemistry. 282(48):35269-35278. Abstract
BarlowJN, SteyaertJ.  2007.  Examination of the mechanism and energetic contribution of leaving group activation in the purine-specific nucleoside hydrolase from Trypanosoma vivax. BBA. 1774(11):1451-1461. Abstract
2006
VandemeulebrouckeA, VerseesW, SteyaertJ, BarlowJN.  2006.  Multiple transients in the pre-steady-state of nucleoside hydrolase reveal complex substrate binding, product base release, and two apparent rates of chemistry. Biochemistry. 45(30):9307-9318. Abstract
VerseesW, BarlowJ, SteyaertJ.  2006.  Transition-state complex of the purine-specific nucleoside hydrolase of T. vivax: enzyme conformational changes and implications for catalysis. Journal Molecular Biology. 359(2):331-346. Abstract
2003
VerseesW, SteyaertJ.  2003.  Catalysis by nucleoside hydrolases. Current opinion in structural biology. 13(6):731-738. Abstract
VandemeulebrouckeA, VerseesW, DeVos S, VanHolsbeke E, SteyaertJ.  2003.  Pre-steady-state analysis of the nucleoside hydrolase of Trypanosoma vivax. Evidence for half-of-the-sites reactivity and rate-limiting product release. Biochemistry. 42(44):12902-12908. Abstract
VerseesW, VanHolsbeke E, DeVos S, DecanniereK, ZegersI, SteyaertJ.  2003.  Cloning, preliminary characterization and crystallization of nucleoside hydrolases from Caenorhabditis elegans and Campylobacter jejuni. Acta Crystallographica D. 59(Pt 6):1087-1089. Abstract
2002
MignonP, SteyaertJ, LorisR, GeerlingsP, LoverixS.  2002.  A nucleophile activation dyad in ribonucleases. A combined X-ray crystallographic/ab initio quantum chemical study. Journal Bioogical Chemistry. 277(39):36770-36774. Abstract
2001
LoverixS, SteyaertJ.  2001.  Deciphering the mechanism of RNase T1. 341:305-323.
2000
LoverixS, WinqvistA, StrombergR, SteyaertJ.  2000.  Mechanism of RNase T1: concerted triester-like phosphoryl transfer via a catalytic three-centered hydrogen bond. 7(8):651-658. Abstract
1998
LoverixS, LausG, MartinsJC, WynsL, SteyaertJ.  1998.  Reconsidering the energetics of ribonuclease catalysed RNA hydrolysis. 257(1):286-290. Abstract
ZegersI, LorisR, DehollanderG, FattahHaikal A, PoortmansF, SteyaertJ, WynsL.  1998.  Hydrolysis of a slow cyclic thiophosphate substrate of RNase T1 analyzed by time-resolved crystallography. 5(4):280-283. Abstract
1995
SteyaertJ, EngelborghsY.  1995.  A two-binding-site kinetic model for the ribonuclease-T1-catalysed transesterification of dinucleoside phosphate substrates. 233(1):140-144. Abstract
1994
PletinckxJ, SteyaertJ, ZegersI, ChoeHW, HeinemannU, WynsL.  1994.  Crystallographic study of Glu58Ala RNase T1 x 2'-guanosine monophosphate at 1.9-A resolution. Biochemistry. 33(7):1654-1662. Abstract
1993
SteyaertJ, WynsL.  1993.  Functional interactions among the His40, Glu58 and His92 catalysts of ribonuclease T1 as studied by double and triple mutants. 229(3):770-781. Abstract

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