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2008
CandelAM, van NulandNA, Martin-SierraFM, MartinezJC, Conejero-LaraF.  2008.  Analysis of the thermodynamics of binding of an SH3 domain to proline-rich peptides using a chimeric fusion protein. 377(1):117-135. Abstract
2007
Van MolleI, JoensuuJJ, ButsL, PanjikarS, KotiahoM, BouckaertJ, WynsL, Niklander-TeeriV, De Greve H.  2007.  Chloroplasts assemble the major subunit FaeG of Escherichia coli F4 (K88) fimbriae to strand-swapped dimers. Journal Molecular Biology. 368(3):791-799. Abstract
RoosG, Garcia-PinoA, VanBelle K, BrosensE, WahniK, VandenbusscheG, WynsL, LorisR, MessensJ.  2007.  The conserved active site proline determines the reducing power of Staphylococcus aureus thioredoxin. J. Mol. Biol.. 368(3):800-811. Abstract
CasaresS, AbE, EshuisH, Lopez-MayorgaO, van NulandNA, Conejero-LaraF.  2007.  The high-resolution NMR structure of the R21A Spc-SH3:P41 complex: understanding the determinants of binding affinity by comparison with Abl-SH3. 7:22. Abstract
2006
RoosG, BrosensE, WahniK, DesmyterA, SpinelliS, WynsL, MessensJ, LorisR.  2006.  Combining site-specific mutagenesis and seeding as a strategy to crystallize 'difficult' proteins: the case of Staphylococcus aureus thioredoxin. Acta Crystallogr. Sect F Struct. Biol. Cryst. Commun.. 62(Pt 12):1255-1258. Abstract
SibilleN, FavierA, AzuagaAI, GanshawG, BottR, BonvinAM, BoelensR, van NulandNA.  2006.  Comparative NMR study on the impact of point mutations on protein stability of Pseudomonas mendocina lipase. 15(8):1915-1927. Abstract
RoosG, ButsL, VanBelle K, BrosensE, GeerlingsP, LorisR, WynsL, MessensJ.  2006.  Interplay between ion binding and catalysis in the thioredoxin-coupled arsenate reductase family. J. Mol. Biol.. 360(4):826-838. Abstract
VerseesW, BarlowJ, SteyaertJ.  2006.  Transition-state complex of the purine-specific nucleoside hydrolase of T. vivax: enzyme conformational changes and implications for catalysis. Journal Molecular Biology. 359(2):331-346. Abstract
RoosG, LoverixS, BrosensE, VanBelle K, WynsL, GeerlingsP, MessensJ.  2006.  The activation of electrophile, nucleophile and leaving group during the reaction catalysed by pI258 arsenate reductase. Chembiochem.. 7(6):981-989. Abstract
2005
Dao-ThiMH, VanMelderen L, DeGenst E, AfifH, ButsL, WynsL, LorisR.  2005.  Molecular basis of gyrase poisoning by the addiction toxin CcdB. 348(5):1091-1102. Abstract
TielkerD, HackerS, LorisR, StrathmannM, WingenderJ, WilhelmS, RosenauF, JaegerKE.  2005.  Pseudomonas aeruginosa lectin LecB is located in the outer membrane and is involved in biofilm formation. 151(Pt 5):1313-1323. Abstract
LoverixS, GeerlingsP, McNaughtonM, AugustynsK, VandemeulebrouckeA, SteyaertJ, VerseesW.  2005.  Substrate-assisted leaving group activation in enzyme-catalyzed N-glycosidic bond cleavage. J. Biol. Chem. 280(15):14799-14802. Abstract
DumoulinM, CanetD, LastAM, PardonE, ArcherDB, MuyldermansS, WynsL, MatagneA, RobinsonCV, RedfieldC, DobsonCM.  2005.  Reduced global cooperativity is a common feature underlying the amyloidogenicity of pathogenic lysozyme mutations. Nature. 346(3):773-788. Abstract
2004
WallJS, GuptaV, WilkersonM, SchellM, LorisR, AdamsP, SolomonA, StevensF, DealwisC.  2004.  Structural basis of light chain amyloidogenicity: comparison of the thermodynamic properties, fibrillogenic potential and tertiary structural features of four Vlambda6 proteins. 17(4):323-331. Abstract
MessensJ, VanMolleI, VanhaesebrouckP, LimbourgM, VanBelle K, WahniK, MartinsJC, LorisR, WynsL.  2004.  How thioredoxin can reduce a buried disulphide bond. J. Mol. Biol.. 339(3):527-537. Abstract
MessensJ, VanMolleI, VanhaesebrouckP, VanBelle K, WahniK, MartinsJC, WynsL, LorisR.  2004.  The structure of a triple mutant of pI258 arsenate reductase from Staphylococcus aureus and its 5-thio-2-nitrobenzoic acid adduct. Acta Crystallogr. D Biol. Crystallogr.. 60(Pt 6):1180-1184. Abstract
VerseesW, LoverixS, VandemeulebrouckeA, GeerlingsP, SteyaertJ.  2004.  Leaving group activation by aromatic stacking: an alternative to general acid catalysis. J. Mol. Biol. 338(1):1-6. Abstract
2003
DerixNM, WechselbergerRW, van der HorstMA, HellingwerfKJ, BoelensR, KapteinR, van NulandNA.  2003.  Lack of negative charge in the E46Q mutant of photoactive yellow protein prevents partial unfolding of the blue-shifted intermediate. 42(49):14501-14506. Abstract
VerseesW, SteyaertJ.  2003.  Catalysis by nucleoside hydrolases. Current opinion in structural biology. 13(6):731-738. Abstract
DumoulinM, LastAM, DesmyterA, DecanniereK, CanetD, LarssonG, SpencerA, ArcherDB, SasseJ, MuyldermansS, WynsL, RedfieldC, MatagneA, RobinsonCV, DobsonCM.  2003.  A camelid antibody fragment inhibits the formation of amyloid fibrils by human lysozyme. 424(6950):783-788. Abstract
LorisR, MarianovskyI, LahJ, LaeremansT, Engelberg-KulkaH, GlaserG, MuyldermansS, WynsL.  2003.  Crystal structure of the intrinsically flexible addiction antidote MazE. 278(30):28252-28257. Abstract
CanetD, LyonCE, ScheekRM, RobillardGT, DobsonCM, HorePJ, van NulandNA.  2003.  Rapid formation of non-native contacts during the folding of HPr revealed by real-time photo-CIDNP NMR and stopped-flow fluorescence experiments. 330(2):397-407. Abstract
LahN, LahJ, ZegersI, WynsL, MessensJ.  2003.  Specific potassium binding stabilizes pI258 arsenate reductase from Staphylococcus aureus. J. Biol. Chem.. 278(27):24673-24679. Abstract
AzuagaAI, CanetD, SmeenkG, BerendsR, TitgemeijerF, DuurkensR, MateoPL, ScheekRM, RobillardGT, DobsonCM, van NulandNA.  2003.  Characterization of single-tryptophan mutants of histidine-containing phosphocarrier protein: evidence for local rearrangements during folding from high concentrations of denaturant. 42(17):4883-4895. Abstract
2002
MessensJ, MartinsJC, VanBelle K, BrosensE, DesmyterA, DeGieter M, WieruszeskiJM, WillemR, WynsL, ZegersI.  2002.  All intermediates of the arsenate reductase mechanism, including an intramolecular dynamic disulfide cascade. Proc. Natl. Acad. Sci. USA. 99(13):8506-8511. Abstract

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