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Found 8 results

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Filters: keyword is N-Glycosyl Hydrolases  [Clear All Filters]
2007
GoeminneA, McNaughtonM, BalG, SurpateanuG, VanDerV, DeProl S, VerseesW, SteyaertJ, ApersS, HaemersA, AugustynsK.  2007.  1,2,3-Triazolylalkylribitol derivatives as nucleoside hydrolase inhibitors. Bioorg. & Med. Chem. Lett.. 17(9):2523-2526. Abstract
2006
VandemeulebrouckeA, VerseesW, SteyaertJ, BarlowJN.  2006.  Multiple transients in the pre-steady-state of nucleoside hydrolase reveal complex substrate binding, product base release, and two apparent rates of chemistry. Biochemistry. 45(30):9307-9318. Abstract
VerseesW, BarlowJ, SteyaertJ.  2006.  Transition-state complex of the purine-specific nucleoside hydrolase of T. vivax: enzyme conformational changes and implications for catalysis. Journal Molecular Biology. 359(2):331-346. Abstract
2005
HuysmansG, RanquinA, WynsL, SteyaertJ, VanGelder P.  2005.  Encapsulation of therapeutic nucleoside hydrolase in functionalised nanocapsules. J Control Release. 102(1):171-179. Abstract
HuysmansG, RanquinA, WynsL, SteyaertJ, VanGelder P.  2005.  Encapsulation of therapeutic nucleoside hydrolase in functionalised nanocapsules. 102(1):171-179. Abstract
2004
VerseesW, LoverixS, VandemeulebrouckeA, GeerlingsP, SteyaertJ.  2004.  Leaving group activation by aromatic stacking: an alternative to general acid catalysis. J. Mol. Biol. 338(1):1-6. Abstract
2003
VerseesW, SteyaertJ.  2003.  Catalysis by nucleoside hydrolases. Current opinion in structural biology. 13(6):731-738. Abstract
VandemeulebrouckeA, VerseesW, DeVos S, VanHolsbeke E, SteyaertJ.  2003.  Pre-steady-state analysis of the nucleoside hydrolase of Trypanosoma vivax. Evidence for half-of-the-sites reactivity and rate-limiting product release. Biochemistry. 42(44):12902-12908. Abstract