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2009
ElHajjaji H, DumoulinM, MatagneA, ColauD, RoosG, MessensJ, ColletJF.  2009.  The zinc center influences the redox and thermodynamic properties of Escherichia coli thioredoxin 2. 386(1):60-71. Abstract
2007
VerseesW, SpaepenS, WoodMD, LeeperFJ, VanderleydenJ, SteyaertJ.  2007.  Molecular mechanism of allosteric substrate activation in a thiamine diphosphate-dependent decarboxylase. Journal Biological Chemistry. 282(48):35269-35278. Abstract
BarlowJN, SteyaertJ.  2007.  Examination of the mechanism and energetic contribution of leaving group activation in the purine-specific nucleoside hydrolase from Trypanosoma vivax. BBA. 1774(11):1451-1461. Abstract
Garcia-PinoA, ButsL, WynsL, ImbertyA, LorisR.  2007.  How a plant lectin recognizes high mannose oligosaccharides. 144(4):1733-1741. Abstract
RoosG, Garcia-PinoA, VanBelle K, BrosensE, WahniK, VandenbusscheG, WynsL, LorisR, MessensJ.  2007.  The conserved active site proline determines the reducing power of Staphylococcus aureus thioredoxin. J. Mol. Biol.. 368(3):800-811. Abstract
VerseesW, SpaepenS, VanderleydenJ, SteyaertJ.  2007.  The crystal structure of phenylpyruvate decarboxylase from Azospirillum brasilense at 1.5 A resolution. Implications for its catalytic and regulatory mechanism. FEBS J. 274(9):2363-2375. Abstract
De GreveH, WynsL, BouckaertJ.  2007.  Combining sites of bacterial fimbriae. Current opinion in structural biology. 17(5):506-512. Abstract
2006
RoosG, BrosensE, WahniK, DesmyterA, SpinelliS, WynsL, MessensJ, LorisR.  2006.  Combining site-specific mutagenesis and seeding as a strategy to crystallize 'difficult' proteins: the case of Staphylococcus aureus thioredoxin. Acta Crystallogr. Sect F Struct. Biol. Cryst. Commun.. 62(Pt 12):1255-1258. Abstract
Garcia-PinoA, ButsL, WynsL, LorisR.  2006.  Interplay between metal binding and cis/trans isomerization in legume lectins: structural and thermodynamic study of P. angolensis lectin. 361(1):153-167. Abstract
VandemeulebrouckeA, VerseesW, SteyaertJ, BarlowJN.  2006.  Multiple transients in the pre-steady-state of nucleoside hydrolase reveal complex substrate binding, product base release, and two apparent rates of chemistry. Biochemistry. 45(30):9307-9318. Abstract
RoosG, ButsL, VanBelle K, BrosensE, GeerlingsP, LorisR, WynsL, MessensJ.  2006.  Interplay between ion binding and catalysis in the thioredoxin-coupled arsenate reductase family. J. Mol. Biol.. 360(4):826-838. Abstract
ButsL, Garcia-PinoA, WynsL, LorisR.  2006.  Structural basis of carbohydrate recognition by a Man(alpha1-2)Man-specific lectin from Bowringia milbraedii. 16(7):635-640. Abstract
VerseesW, BarlowJ, SteyaertJ.  2006.  Transition-state complex of the purine-specific nucleoside hydrolase of T. vivax: enzyme conformational changes and implications for catalysis. Journal Molecular Biology. 359(2):331-346. Abstract
ButsL, Garcia-PinoA, ImbertyA, AmiotN, BoonsGJ, BeeckmansS, VerseesW, WynsL, LorisR.  2006.  Structural basis for the recognition of complex-type biantennary oligosaccharides by Pterocarpus angolensis lectin. 273(11):2407-2420. Abstract
2005
SaerensD, PellisM, LorisR, PardonE, DumoulinM, MatagneA, WynsL, MuyldermansS, ConrathK.  2005.  Identification of a universal VHH framework to graft non-canonical antigen-binding loops of camel single-domain antibodies. 352(3):597-607. Abstract
Dao-ThiMH, VanMelderen L, DeGenst E, AfifH, ButsL, WynsL, LorisR.  2005.  Molecular basis of gyrase poisoning by the addiction toxin CcdB. 348(5):1091-1102. Abstract
DeGenst E, SilenceK, GhahroudiMA, DecanniereK, LorisR, KinneJ, WynsL, MuyldermansS.  2005.  Strong in vivo maturation compensates for structurally restricted H3 loops in antibody repertoires. 280(14):14114-14121. Abstract
AzuagaAI, NeiraJL, van NulandNA.  2005.  HPr as a model protein in structure, interaction, folding and stability studies. 12(2):123-137. Abstract
2004
DeGenst E, HandelbergF, VanMeirhaeghe A, VynckS, LorisR, WynsL, MuyldermansS.  2004.  Chemical basis for the affinity maturation of a camel single domain antibody. 279(51):53593-53601. Abstract
TzakosAG, FuchsP, van NulandNA, TroganisA, TseliosT, DeraosS, MatsoukasJ, GerothanassisIP, BonvinAM.  2004.  NMR and molecular dynamics studies of an autoimmune myelin basic protein peptide and its antagonist: structural implications for the MHC II (I-Au)-peptide complex from docking calculations. 271(16):3399-3413. Abstract
MessensJ, VanMolleI, VanhaesebrouckP, LimbourgM, VanBelle K, WahniK, MartinsJC, LorisR, WynsL.  2004.  How thioredoxin can reduce a buried disulphide bond. J. Mol. Biol.. 339(3):527-537. Abstract
VerseesW, LoverixS, VandemeulebrouckeA, GeerlingsP, SteyaertJ.  2004.  Leaving group activation by aromatic stacking: an alternative to general acid catalysis. J. Mol. Biol. 338(1):1-6. Abstract
LorisR, VanWalleI, De GreveH, BeeckmansS, DeboeckF, WynsL, BouckaertJ.  2004.  Structural basis of oligomannose recognition by the Pterocarpus angolensis seed lectin. J. Mol. Biol.. 335(5):1227-1240. Abstract
2003
DerixNM, WechselbergerRW, van der HorstMA, HellingwerfKJ, BoelensR, KapteinR, van NulandNA.  2003.  Lack of negative charge in the E46Q mutant of photoactive yellow protein prevents partial unfolding of the blue-shifted intermediate. 42(49):14501-14506. Abstract
VerseesW, SteyaertJ.  2003.  Catalysis by nucleoside hydrolases. Current opinion in structural biology. 13(6):731-738. Abstract

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