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Found 24 results

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2007
AdriaensenC, De GreveH, TianJQ, De CraeyeS, GubbelsE, EeckhautV, Van ImmerseelF, DucatelleR, KumarM, HernalsteensJP.  2007.  A live Salmonella enterica serovar Enteritidis vaccine allows serological differentiation between vaccinated and infected animals. 75(5):2461-2468. Abstract
2006
DeGenst E, SilenceK, DecanniereK, ConrathK, LorisR, KinneJ, MuyldermansS, WynsL.  2006.  Molecular basis for the preferential cleft recognition by dromedary heavy-chain antibodies. 103(12):4586-4591. Abstract
2005
SaerensD, PellisM, LorisR, PardonE, DumoulinM, MatagneA, WynsL, MuyldermansS, ConrathK.  2005.  Identification of a universal VHH framework to graft non-canonical antigen-binding loops of camel single-domain antibodies. 352(3):597-607. Abstract
ConrathK, VinckeC, StijlemansB, SchymkowitzJ, DecanniereK, WynsL, MuyldermansS, LorisR.  2005.  Antigen binding and solubility effects upon the veneering of a camel VHH in framework-2 to mimic a VH. 350(1):112-125. Abstract
DeGenst E, SilenceK, GhahroudiMA, DecanniereK, LorisR, KinneJ, WynsL, MuyldermansS.  2005.  Strong in vivo maturation compensates for structurally restricted H3 loops in antibody repertoires. 280(14):14114-14121. Abstract
DumoulinM, CanetD, LastAM, PardonE, ArcherDB, MuyldermansS, WynsL, MatagneA, RobinsonCV, RedfieldC, DobsonCM.  2005.  Reduced global cooperativity is a common feature underlying the amyloidogenicity of pathogenic lysozyme mutations. Nature. 346(3):773-788. Abstract
2004
TzakosAG, FuchsP, van NulandNA, TroganisA, TseliosT, DeraosS, MatsoukasJ, GerothanassisIP, BonvinAM.  2004.  NMR and molecular dynamics studies of an autoimmune myelin basic protein peptide and its antagonist: structural implications for the MHC II (I-Au)-peptide complex from docking calculations. 271(16):3399-3413. Abstract
2003
DumoulinM, LastAM, DesmyterA, DecanniereK, CanetD, LarssonG, SpencerA, ArcherDB, SasseJ, MuyldermansS, WynsL, RedfieldC, MatagneA, RobinsonCV, DobsonCM.  2003.  A camelid antibody fragment inhibits the formation of amyloid fibrils by human lysozyme. 424(6950):783-788. Abstract
TzakosAG, BonvinAM, TroganisA, CordopatisP, AmzelML, GerothanassisIP, van NulandNA.  2003.  On the molecular basis of the recognition of angiotensin II (AII). NMR structure of AII in solution compared with the X-ray structure of AII bound to the mAb Fab131. 270(5):849-860. Abstract
2002
DesmyterA, SpinelliS, PayanF, LauwereysM, WynsL, MuyldermansS, CambillauC.  2002.  Three camelid VHH domains in complex with porcine pancreatic alpha-amylase. Inhibition and versatility of binding topology. 277(26):23645-23650. Abstract
DumoulinM, ConrathK, VanMeirhaeghe A, MeersmanF, HeremansK, FrenkenLG, MuyldermansS, WynsL, MatagneA.  2002.  Single-domain antibody fragments with high conformational stability. 11(3):500-515. Abstract
2001
DecanniereK, TransueTR, DesmyterA, MaesD, MuyldermansS, WynsL.  2001.  Degenerate interfaces in antigen-antibody complexes. 313(3):473-478. Abstract
ConrathKE, LauwereysM, GalleniM, MatagneA, FrereJM, KinneJ, WynsL, MuyldermansS.  2001.  Beta-lactamase inhibitors derived from single-domain antibody fragments elicited in the camelidae. 45(10):2807-2812. Abstract
DesmyterA, DecanniereK, MuyldermansS, WynsL.  2001.  Antigen specificity and high affinity binding provided by one single loop of a camel single-domain antibody. 276(28):26285-26290. Abstract
MuyldermansS, CambillauC, WynsL.  2001.  Recognition of antigens by single-domain antibody fragments: the superfluous luxury of paired domains. 26(4):230-235. Abstract
2000
NguyenVK, HamersR, WynsL, MuyldermansS.  2000.  Camel heavy-chain antibodies: diverse germline V(H)H and specific mechanisms enlarge the antigen-binding repertoire. 19(5):921-930. Abstract
1999
NguyenVK, HamersR, WynsL, MuyldermansS.  1999.  Loss of splice consensus signal is responsible for the removal of the entire C(H)1 domain of the functional camel IGG2A heavy-chain antibodies. 36(8):515-524. Abstract
DecanniereK, DesmyterA, LauwereysM, GhahroudiMA, MuyldermansS, WynsL.  1999.  A single-domain antibody fragment in complex with RNase A: non-canonical loop structures and nanomolar affinity using two CDR loops. 7(4):361-370. Abstract
1998
TransueTR, DeGenst E, GhahroudiMA, WynsL, MuyldermansS.  1998.  Camel single-domain antibody inhibits enzyme by mimicking carbohydrate substrate. 32(4):515-522. Abstract
LauwereysM, ArbabiGhahroudi M, DesmyterA, KinneJ, HolzerW, DeGenst E, WynsL, MuyldermansS.  1998.  Potent enzyme inhibitors derived from dromedary heavy-chain antibodies. 17(13):3512-3520. Abstract
1997
VuKB, GhahroudiMA, WynsL, MuyldermansS.  1997.  Comparison of llama VH sequences from conventional and heavy chain antibodies. 34(16-17):1121-1131. Abstract
ArbabiGhahroudi M, DesmyterA, WynsL, HamersR, MuyldermansS.  1997.  Selection and identification of single domain antibody fragments from camel heavy-chain antibodies. 414(3):521-526. Abstract
BertelsA, JourquinJ, BuysN, VanZeveren A, De GreveH, HernalsteensJP, BouquetY.  1997.  Selection of swine resistant to F4-positive Escherichia coli. Adv. Exp. Med. Biol.. 412:427-429.
1996
DesmyterA, TransueTR, GhahroudiMA, ThiMH, PoortmansF, HamersR, MuyldermansS, WynsL.  1996.  Crystal structure of a camel single-domain VH antibody fragment in complex with lysozyme. 3(9):803-811. Abstract