PhD theses

The table below gives an overview of all the PhD theses written at Structural Biology Brussels. You can view the .pdf file by clicking on the pdf icon of the right column of the table.

Enjoy!

2010
Caroline De Vocht	Polymeric Nanoreactors for Use in Enzyme Replacement Therapy
2009
Natalie De Jonge	Mechanism of Gyrase Binding and Rejuvenation by the ccd Proteins
2008
Kris Pauwels	Structure-function Relationship of the Lipase-foldase Complex of Burkholderia glumae
An Ranquin	Therapeutic Nanoreactors: Combining Chemistry and Biology in a Novel Copolymer Drug Delivery System
Mike Sleutel	Growth Kinetics and Mass Transport Phenomena During Protein Crystallization
An Vandemeulebroucke	Kinetic Analysis of the Purine Nucleoside Hydrolase Mechanism
2007
Goedele Roos	Theory Meets Experiment: a Combined Quantum Chemical-Experimental Study of the Reaction Mechanism pf pI258 Arsenate Reductase
2005
Pierre Mignon	Quantum Chemical Study of the Interplay Between Non-covalent Interactions in Biomolecules
Ivo Van Walle	Algn-m, a Platform for Sensitive and Highly Specific Multiple Sequence Alignment
2004
Lieven Buts	Analysis of Protein-Carbohydrate Interactions using Macromolecular Crystallography and Biophysical Affinity Measurements
Erwin De Genst	Molecular Recognition and Maturation of Camelid Heavy Chain Antibodies
Camelia Mihai	Study of the Protein-Sugar Interaction in Chitin Binding Elderberry Lectin by Nuclear Resonance Spectroscopy
Maria Teresa Serrao	Anti-hapten Chain Antibodies from Camelidae
2002
Stefan De Vos	Contribution to the Understanding of the Conformational Stability of Ribonuclease T1
Joris Messens	Biochemical and Structural Characterisation of Arsenate Reductase from Staphylococcus aureus
Wim Versees	Structure and Function of the Inosine-adenosine-guanosine Preferring Nucleoside Hydrolase from Trypanosoma vivax
2000
Stefan Loverix	Analysis of the Transphosphorylation Reaction Catalyzed by RNase T1 via Site-directed Mutagenesis and Chemically Modified Substrates
Caritas Tibazarwa	Characterisation of the Regulatory Components Controlling Resistance to Cobalt and Nickel in Ralstonia ex alcaligenes eutrophus CH34
1999
Vu Khoa Bang	Llama Antibodies and Engineering of Single-Domain Antibody Fragments
Thomas Hamelryck	Structural Studies of Four Members of the Legume Lectin Family: Phytohemagglutinin-L, Arcelin-5, Dolichos biflorus Seed Lectin and Dolichos biflorus Stem and Leaf Lectin
Ulrike Langhorst	Analysis of Protein-Water Interactions Using RNase T1 as a Model System
1998
Jan Doumen	Analysing the Structure and Function of Ribonuclease T1 Using Site-Directed Mutagenesis, X-ray Crystallography and Substrate Mimicks
Vibha Gupta	Recombinant Rat Ribonucleases A: Sequence-Structure-Function Relationships in the Ribonuclease A Superfamily
Gaynor Hayburn	Characterization of the Arsenate Reductase Enzymes from Staphylococcal Bacteria
1997
Anja Gillis	Siderophores of Alcaligenes eutrophus: Characterization, Regulation of the Biosynthesis and Interaction with Heavy Metals
1996
Julie Bouckaert	Mapping the Structural Features of Metal and Carbohydrate Binding to Concanavalin A
Mehdi Arbabi Ghahroudi	Generation and Characterisation of Phage-Displayed Camel Single-Domain Antibodies
1994
Remy Loris	On the Structure and Function of lentil (Lens culinaris) Lectin
Ingrid Zegers	A Contribution to the Structural Analysis of RNase and RNase T1
1992
Geert Meersseman	Dynamics of Chromatin in Simple Model Systems
Jan Steyaert	Analysis of the Structure-Function Relation of RNase T1 by Site-Directed Mutagenesis
1991
Alain Segers	Roles of Histones H1 and H5 in the Structural Organization of Oligonucleosomes
1988
Sari Pennings	Protein-DNA Interactions in Mononucleosomes
1978
Lode Wyns	Contribution to the Study of Histones, Nucleosomes and Chromatin